- It is the responsibility of IEC to evaluate biomedical research, help safeguard the dignity, rights, safety and welfare of all current and potential research participants and assess the relevance, rationale, design and methodology of the proposed studies. Special attention to research that may include vulnerable people must be taken.
- A cardinal principle of research involving human beings is to respect personal dignity. The goals of the research, while important, should never overcome health, welfare and care of research participants. Take special care not to allow the use of subjects as "means" for, but always as an "end" to obtain knowledge.
- The IEC must take into consideration the principle of distributive justice and justice with reciprocity. Distributive justice requires that benefits and burdens of research be distributed fairly among all groups and classes in society, taking into account their age, sex, economic status, cultural and ethnic considerations. The reciprocal justice refers to what is owed to the participating subject and community for their contribution in the generation of scientific knowledge.
- The IEC is responsible for acting in the full interest of potential research participants and communities involved, taking into account interests and needs of researchers and regulatory agency requirements and applicable laws.
- The IEC is responsible for evaluating the proposed research before it begins. It must also ensure regular evaluation and monitoring of development studies who received a positive decision at appropriate intervals according to the degree of risk to people. This evaluation will be concurrent with the development of study. IEC will also perform result assessment activities of approved studies periodically and generate information, which should be disseminated in the medical community and in general, to national regulatory agencies and, if applicable, international agencies.
- The IEC must supervise all research involving human subjects conducted by doctors, students, staff, or when using any information property of an institution and / or patient not in the public domain related to research in human subjects.
- The IEC has the authority to approve, reject or request modification of research protocols. The Committee may also suspend or terminate the approval granted to a research activity.